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Bioinformatics Scientist – Assay DesignSouth San Francisco, California, US

Mission Bio

Bioinformatics Scientist – Assay Design

South San Francisco | California | US

We are looking for a talented, hardworking and passionate scientist to join our team. Your job will be to work with a team of bioinformatics scientists to design multiplexed amplification panels and analyze next generation sequencing data to support our single cell genomics platform. If you want to work towards moving precision medicine forward and work among smart scientists and engineers who are pioneers of single cell genomics, here is your opportunity.

  • Will design highly multiplexed amplification panels capable of interrogating genes and mutations
  • Will develop tools and algorithm for amplicon design
  • Will analyze NGS data from amplicon design and targeted sequencing panels to improve and optimize the pipelines
  • Will interrogate clinical databases to identify genes and variations associated with relevant clinical indications
  • Will collaborate with internal project teams and with external organizations
  • Will provide written documentation and specifications of bioinformatic workflows and requirements

Basic qualifications
  • PhD or Masters in Bioinformatics, Computational biology, Genomics
  • Experience with PCR primer design
  • Experience with NGS data analysis
  • Expertise in Python or Perl
  • Proficiency in Linux environment
  • Strong knowledge of Bioinformatics tools and databases (e.g. GATK, BWA, Samtools, Bowtie, UCSC browser, RefSeq, dbSNP, ClinVar, TCGA, COSMIC)
  • Strong understanding of genomics, genetics, and sequencing technologies
  • Collaborative

Preferred qualifications
  • Industry experience and/or experience working in a deliverable focused environment
  • Experience with R and statistical analysis
  • Knowledge of single cell genomics
  • Experience in cancer genomics

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